Introduction

BioFix C is BioGnost’s modification of Carnoy’s fixative that provides the same results like traditional Carnoy’s fixative. BioFix C is a fixative that penetrates the tissues rapidly and is excellent for fixation of glycogens, Nissl’s granules, and nuclear materials. Since it an anhydrous fixative based on alcohol, BioFix C simultaneously fixates and dehydrates. It is recommended for use with samples stained according to AZAN or Congo Red Highman method.

CAUTION: Do not use with samples that contain acid-fast bacteria, because the bacteria will not be stained like acid-fast bacteria after being exposed to BioFIx C. BioFix C also hemolyzes erythrocytes and dissolves granules and pigments soluble in acid media. If the samples are immersed in BioFix C for a prolonged period of time, excessive compression and hardening of samples may occur. Not recommended for use in immunohistochemistry.