Hematoxylin HP, Pap 1B

Product Description

Hematoxylin modified according to Harris for intensive nuclear staining according to Papanicolaou. Reagent for progressive and regressive staining in exfoliative cytology, with formulation stronger than Hematoxylin HP, Pap 1A.

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BioGnost’s Hematoxylin HP, Pap 1B is one of formulations of hematoxylin used in cytology for a more precise nuclear cell staining. Unlike Hematoxylin H which is used in histology, Hematoxylin HP, Pap 1B is ideal for intensive staining cytology smears using progressive and regressive methods. Hematoxylin is extracted from logwood (Haematoxylon campechianum L.). Hematoxylin oxidates to hematein and binds with metal ions (mordants), hematein turns into irreplaceable nuclear dye. Positively charged hematein-mordant complex then binds with negatively charged phosphate ions of the DNA’s nucleus, creating characteristic blue coloration. BioGnost’s Hematoxylin HP, Pap 1B is a specific concentrated hematoxylin solution used for staining chromatins of both normal and abnormal cytology smears. They stain nuclear membrane, nucleoplasm and nucleolus exceptionally well. Test samples can be gynecological and non-gynecological, such as sputum, urine, and cytological puncture samples. In order to obtain optimal staining results, BioGnost’s Hematoxylin HP, Pap 1B properties are completely in accordance with other BioGnost’s reagents used for cytological staining acc. to Papanicolaou – OG-6, Pap 2A reagent, EA 31, Pap 3A reagent, as well as alternative counterstain polychromatic stains, such as EA 50, Pap 3B reagent, EA 65, Pap 3C reagent, and EA 65, Pap 3D reagent.

Technical Data

Chemical name:
Catalogue number: HEMHP1B-OT-X**

Available volumes:
100 mL
500 mL
1 L
2,5 L

Storing, stability and expiry date:

Transport information:
Transporting/shipment by road (ADR) - Not classified
Transporting/shipment by sea (IMDG) - Not classified
Transporting/shipment by air (ICAO-TI/IATA-DGR) - Not classified

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