Introduction

Scott’s solution is a histological reagent that substitutes tap water and enables fast and accurate bluing of nuclear chromatin and membranes of the cell nucleus. Because of its hardness and alkalinity, tap water changes the color of the nuclei previously stained with hematoxylin. Many hematoxylin modifications are used in histology and cytology for precise nuclear staining. By using BioGnost’s Scott’s solution, sample tissues no longer get degraded after adhering to glass slide (unlike other bluing reagents). Its synonym is Scott’s tap water substitute.